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Mouse Serine/Threonine-Protein Kinase ATR (ATR) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Serine/Threonine-Protein Kinase ATR (ATR) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse ATR in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
Serine/threonine-protein kinase ATR is a serine/threonine protein kinase that triggers checkpoint signaling in response to genotoxic stresses such as ionizing radiation, ultraviolet light, or DNA replication stalling, acting as a DNA damage sensor. In mice, the primary role of ATR is associated with chromosome pairing, recombination, and DNA damage response during meiosis. ATR is crucial in mouse meiosis, especially for the pairing of homologous chromosomes (synapsis) and recombination. Additionally, ATR is vital for maintaining the integrity of chromosome axes. The absence of ATR results in the death of spermatogenic cells during mid-pachynema, underscoring its essential role in the normal progression of meiosis.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.