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Mouse Neurotensin Receptor 1, High Affinity (NTSR1) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Neurotensin Receptor 1, High Affinity (NTSR1) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse NTSR1 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
Neurotensin receptor type 1 is a G-protein coupled receptor for the tridecapeptide neurotensin (NTS), and its signaling involves G proteins that activate a phosphatidylinositol-calcium second messenger system. This signaling pathway activates downstream MAP kinases and protects cells from apoptosis. In mice, Ntsr1 is expressed in the ventromedial tegmental area (VTA) and plays a crucial role in regulating energy balance and body weight. Studies indicate that mice lacking Ntsr1 exhibit increased appetite and weight gain, suggesting that Ntsr1 helps maintain body weight stability by suppressing eating and promoting physical activity.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Perez-Bonilla, Patricia et al. "Developmental or adult-onset deletion of neurotensin receptor-1 from dopamine neurons differentially reduces body weight." Frontiers in neuroscience vol. 16 874316. 23 Sep. 2022.