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Mouse Mitofusin 1 (MFN1) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Mitofusin 1 (MFN1) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse MFN1 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
Mitofusin-1 is a GTPase located in the mitochondrial outer membrane, essential for mediating mitochondrial clustering and fusion, potentially involving significant rearrangement of coiled coil domains. In mice, Mfn1 is involved in mitochondrial fusion, metabolic regulation, cell fate determination, and disease-related processes. In Alzheimer's disease model mice, Mfn1 expression increases, potentially linked to its role in neuronal synaptic plasticity and mitochondrial function. In mouse oocytes, the absence of Mfn1 leads to accelerated oocyte apoptosis and infertility, indicating its critical role in mitochondrial function and oocyte development.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Wang, Shanshan et al. "Synapsin-Promoted Caveolin-1 Overexpression Maintains Mitochondrial Morphology and Function in PSAPP Alzheimer's Disease Mice." Cells vol. 10,9 2487. 20 Sep. 2021.