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Mouse Plasminogen Activator Inhibitor 2 (PAI2) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Plasminogen Activator Inhibitor 2 (PAI2) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse PAI2 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
Plasminogen activator inhibitor 2 (PAI-2), primarily produced by macrophages, inhibits urokinase-type plasminogen activator and differs from the endothelial cell-derived PAI-1. PAI-2 is not essential for normal development or survival in mice. In a mouse model of prostate cancer, the 213Bi-PAI2 conjugate demonstrated significant anti-tumor activity by prolonging survival and reducing tumor volume. Furthermore, experiments blocking PAI-2 revealed its crucial role in tumor growth, as its inhibition can lead to complete tumor suppression. PAI-2 is also involved in immune regulation and cytoprotection; for instance, in a Mycobacterium tuberculosis infection model, PAI-2 was found to protect host cells from infection.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.