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Mouse Interferon Regulatory Factor 3 (IRF3) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Interferon Regulatory Factor 3 (IRF3) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse IRF3 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
Interferon regulatory factor 3 (IRF3) is a crucial transcriptional regulator of type I interferon (IFN)-dependent immune responses, playing a vital role in the innate immune defense against DNA and RNA viruses. It governs the transcription of type I IFN genes (IFN-alpha and IFN-beta) and interferon-stimulated genes (ISG) by binding to the interferon-stimulated response element (ISRE) in their promoters. In mice, IRF3 fulfills a wide range of functions including immune defense, inflammation regulation, metabolic regulation, cardiovascular protection, and tumor suppression. In a model of liver injury induced by a high-fat diet, the non-transcriptional role of IRF3 helps protect the liver from damage by regulating specific immune cell populations, such as Ly6C low monocytes.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.