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Mouse Inositol Polyphosphate-4-Phosphatase Type I 107kDa (INPP4A) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Inositol Polyphosphate-4-Phosphatase Type I 107kDa (INPP4A) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse INPP4A in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
Inositol polyphosphate-4-phosphatase type I A facilitates the hydrolysis of the 4-position phosphate in phosphatidylinositol 3,4-bisphosphate, as well as inositol 1,3,4-trisphosphate and inositol 1,4-bisphosphate. INPP4A is crucial for neuroprotection in the mouse brain, particularly within the cerebellum and hippocampus. Research indicates that knockout or mutation of the Inpp4a gene results in significant neurodegenerative changes in mice, including cerebellar atrophy and neuronal loss in the hippocampus, which are linked to movement disorders and abnormal behaviors. Furthermore, INPP4A contributes to neuroprotection in the central nervous system by managing glutamate excitotoxicity and preventing excitotoxic neuron death.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.