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Mouse Death-Associated Protein Kinase 2 (DAPK2) ELISA Kit-Sandwich

Name: Mouse Death-Associated Protein Kinase 2 (DAPK2) ELISA Kit-Sandwich
SKU: EK6F961
Rating: 5 (1 reviews)

Cat. No.EK6F961

Product TypeAnimal Immunoassay Kits

Size

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Product Overview

BioVenic Mouse Death-Associated Protein Kinase 2 (DAPK2) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse DAPK2 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich

Specificity The assay kit is specific for Mouse Death-Associated Protein Kinase 2 (DAPK2).

Target Species Mouse

Species Reactivity Mouse

Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 12%

Assay Time Around 90 min

Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids.

Target Information

Death-associated protein kinase 2 (DAPK2) is a calcium/calmodulin-dependent serine/threonine kinase that participates in various cellular signaling pathways influencing cell survival, apoptosis, and autophagy. It regulates both type I apoptotic and type II autophagic cell death signals. In mice, DAPK2 serves a range of biological functions, including roles in erythropoiesis, tubulointerstitial fibrosis, autophagy regulation, granulocyte differentiation and migration, tumor suppression, obesity, and neurovascular function. DAPK2 is expressed in mouse tubulointerstitial cells and promotes fibrosis in a chronic cisplatin-induced nephropathy model. The absence of DAPK2 reduces tubulointerstitial fibrosis, highlighting its profibrotic role in the fibrotic process.

Target/Biomarker Mouse DAPK2

Target Synonym Death-Associated Protein Kinase 2; Dapk2; DAP kinase 2; DAP-kinase-related protein 1 (DRP-1)

Gene ID 13143

UniProt ID Q8VDF3

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

Datasheet

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

Guay, Justin A et al. "Death associated protein kinase 2 is expressed in cortical interstitial cells of the mouse kidney." BMC research notes vol. 7 345. 7 Jun. 2014.