This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Mouse Cytochrome P450 3A4 (CYP3A4) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Cytochrome P450 3A4 (CYP3A4) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse CYP3A4 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
CYP3A4 in mice exhibits complex and multifaceted functions, with its expression and activity in the intestine and liver influenced by various factors such as sex, hormones, environmental pollutants, and disease states. While CYP3A4 expression is relatively low in the mouse liver, it is notably higher in the intestine. For instance, in CYP3A4 transgenic mice (TgCYP3A4), CYP3A4 expression in the small intestine is significantly elevated compared to the liver, resembling the activity levels observed in the human intestine. Additionally, CYP3A4 expression in the liver is regulated by growth hormone (GH) in a sex-dependent manner, with female mice typically displaying higher hepatic CYP3A4 levels than males.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.