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Mouse Cross Linked C-Telopeptide of Type II Collagen (CTXII) ELISA Kit-Competitive

Cat. No.EK5F391

Product TypeAnimal Immunoassay Kits

Size 96T

Product Overview

BioVenic Mouse Cross Linked C-Telopeptide of Type II Collagen (CTXII) ELISA Kit-Competitive is designed for the quantitative determination of Mouse CTXII in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Competitive ELISA method. For research use only.

Specifications

Assay Type ELISA-Competitive
Specificity The assay kit is specific for Mouse Cross Linked C-Telopeptide of Type II Collagen (CTXII).
Target Species Mouse
Species Reactivity Mouse
Detection Range 15.7-1000 pg/mL
Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 12%
Assay Time Around 90 min
Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids.

Target Information

In mice, the function of cross-linked C-telopeptide of type II collagen (CTX-II) is primarily associated with cartilage degradation and the progression of osteoarthritis (OA). CTX-II, a cross-linked product of the C-telopeptide of type II collagen, is widely utilized to evaluate the extent of cartilage degradation. Numerous studies have demonstrated that elevated CTX-II levels closely correlate with the severity of osteoarthritis in patients. Beyond being a crucial biomarker, CTX-II might also contribute to osteoarthritis treatment. For instance, research has shown that the progression of osteoarthritis can be slowed by inhibiting the production or clearance of CTX-II.

Target/Biomarker Mouse CTXII
Target Synonym CTX-II; CTX2

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. M Cristina de Almagro, The Use of Collagen Hydrolysates and Native Collagen in Osteoarthritis. AJBSR. 2020 - 7(6).
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