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Mouse Chloride Intracellular Channel Protein 1 (CLIC1) ELISA Kit-Sandwich

Cat. No.EK6F553

Product TypeAnimal Immunoassay Kits

Size

Product Overview

BioVenic Mouse Chloride Intracellular Channel Protein 1 (CLIC1) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse CLIC1 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich
Specificity The assay kit is specific for Mouse Chloride Intracellular Channel Protein 1 (CLIC1).
Target Species Mouse
Species Reactivity Mouse
Detection Range 0.17-10 ng/mL
Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 12%
Assay Time Around 90 min
Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids.

Target Information

In its soluble form, chloride intracellular channel protein 1 (CLIC1) catalyzes glutaredoxin-like thiol-disulfide exchange reactions using reduced glutathione as the electron donor. It reduces selenite and dehydroascorbate and may serve as an antioxidant in response to oxidative stress. CLIC1 has several vital functions in mice, including maintaining cell membrane stability, regulating oxidative stress response, participating in immune and inflammatory regulation, promoting tumor development and metastasis, regulating angiogenesis, and influencing platelet function. In a mouse model, CLIC1 knockout led to platelet dysfunction, characterized by prolonged clotting time and a diminished platelet response to ADP stimulation.

Target/Biomarker Mouse CLIC1
Target Synonym G6; NCC27; p64CLCP; hRNCC; Chloride channel ABP; Nuclear chloride ion channel 27; Regulatory nuclear chloride ion channel protein
Gene ID 114584
UniProt ID Q9Z1Q5

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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