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Mouse Heparin Cofactor II (HCII) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Heparin Cofactor II (HCII) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse HCII in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
Heparin Cofactor II (HC-II) is a thrombin inhibitor that is activated by glycosaminoglycans, specifically heparin or dermatan sulfate. In the presence of dermatan sulfate, HC-II becomes the main thrombin inhibitor, replacing antithrombin III (AT). It also inhibits chymotrypsin independently of glycosaminoglycans. In mice, the function of HC-II is intricately linked to anticoagulation and the regulation of vascular repair processes. Mouse models have shown that a deficiency in HC-II leads to accelerated thrombosis following arterial endothelial injury and contributes to the development of atherosclerosis and neointimal formation.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.