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Mouse Anti-Rat Forkhead Box P3 (FOXP3) Monoclonal Antibody
Product Overview
BioVenic mouse monoclonal antibody is specific for rat forkhead box p3. It is purified by protein A and protein G. It can be applied to WB, IHC, ICC and IP assays of rat forkhead box p3.
Specifications
Target Information
Rat forkhead box P3 (Foxp3) is a 47-kDa transcription factor specifically expressed in rat regulatory T cells (Tregs) and subsets of activated T cells. As a master regulator of Treg development and function, it controls transcription of Treg-signature genes (e.g., CD25, CTLA-4), maintaining immune tolerance by suppressing effector T cell activation and pro-inflammatory cytokine production. Critical for rat immune homeostasis, it prevents autoimmune diseases and modulates immune responses to pathogens and tumors. Dysregulated expression or function leads to immune dysregulation, inflammation, and autoimmune pathologies. As a definitive Treg marker and central mediator of immune tolerance, rat Foxp3 is a critical target for studying immunology, autoimmune disorders, and tolerance-based immunotherapies.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.