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Mouse Angiotensinogen (AGT) ELISA Kit-Sandwich

Cat. No.EK5F323

Product TypeAnimal Immunoassay Kits

Size

Product Overview

BioVenic Mouse Angiotensinogen (AGT) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse AGT in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich
Specificity The assay kit is specific for Mouse Angiotensinogen (AGT).
Target Species Mouse
Species Reactivity Mouse
Detection Range 7.82-500 ng/mL
Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 12%
Assay Time Around 90 min
Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids.

Target Information

Angiotensinogen is a crucial component of the renin-angiotensin system (RAS), which is a powerful regulator of blood pressure as well as body fluid and electrolyte balance. In mice, the function of angiotensinogen (AGT) is intimately linked to its role in the RAS. AGT knockout mice (Agt-KO) exhibit significant hypotension and increased urine volume, highlighting AGT's vital role in maintaining normal blood pressure. Additionally, AGT expression in the brain influences water and salt balance and affects water intake behavior. For instance, mice with brain-specific overexpression of AGT demonstrate higher water intake and lower blood pressure.

Target/Biomarker Mouse AGT
Target Synonym ANHU; SERPINA8; Angiotensin; Renin Substrate; Serpin Peptidase Inhibitor;Clade A;Member 8(Alpha-1 Antiproteinase;Antitrypsin)
UniProt ID P11859

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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