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Mouse Prostate Specific Antigen (PSA) ELISA Kit-Sandwich

Cat. No.EK6F876

Product TypeAnimal Immunoassay Kits

Size

Product Overview

BioVenic Mouse Prostate Specific Antigen (PSA) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse PSA in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich
Specificity The assay kit is specific for Mouse Prostate Specific Antigen (PSA).
Target Species Mouse
Species Reactivity Mouse
Detection Range 0.17-10 ng/mL
Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 12%
Assay Time Around 90 min
Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids.

Target Information

PSA, a serine protease with trypsin-like activity, functions in semen by promoting sperm motility through the cleavage of seminal gelatin. Additionally, PSA is implicated in the progression, invasion, angiogenesis, and metastasis of prostate cancer. In mice, PSA expression is studied to understand its immune response in prostate cancer. It is expressed in prostate cancer cells and is known to promote bone metastasis in mice. PSA enhances the invasiveness and metastatic potential of tumor cells by increasing the expression of vascular endothelial growth factor (VEGF) and matrix metalloproteinase-9 (MMP-9). Moreover, PSA has been found to encourage the osteogenic differentiation of mesenchymal stem cells (MSCs), accelerating this process by activating the AKT signaling pathway and boosting the expression of CDH11.

Target/Biomarker Mouse PSA
Target Synonym KLK3; APS; KLK2A1; hK3; Kallikrein-3; Kallikrein-Related Peptidase 3; Gamma-seminoprotein

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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