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Mouse 3-Hydroxy-3-Methylglutaryl-CoA Reductase (HMGCR) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse 3-Hydroxy-3-Methylglutaryl-CoA Reductase (HMGCR) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse HMGCR in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
3-Hydroxy-3-methylglutaryl-coenzyme A reductase facilitates the transformation of (3S)-hydroxy-3-methylglutaryl-CoA (HMG-CoA) into mevalonic acid, which is the pivotal step limiting the rate in cholesterol and other isoprenoids' synthesis. This enzyme is essential for maintaining cholesterol balance within cells and is encoded by the HMGCR gene in mice. Research on HMGCR in mice reveals its important role in cholesterol metabolism, disease development and drug treatment. Inhibition of HMGCR improves insulin sensitivity and glucose tolerance while reducing hepatic steatosis and inflammation in high-fat diet-fed mice.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.