Mouse Glucagon Like Peptide 1 Receptor (GLP1R) ELISA Kit-Sandwich

The glucagon-like peptide 1 receptor (GLP-1R) is a G-protein coupled receptor that binds to glucagon-like peptide 1 (GLP-1). Upon ligand binding, it initiates a signaling cascade that activates adenylyl cyclase, leading to an increase in intracellular cAMP levels. In mice, GLP-1R plays a role in regulating metabolism, supporting nervous system function, promoting cardiac health, and potentially providing anti-inflammatory and neuroprotective effects. GLP-1R agonists have been shown to lower postprandial lipid levels, which may be linked to improved insulin sensitivity and reduced fat accumulation. Studies involving GLP-1R knockout mice indicate that GLP-1R has limited effects on controlling food intake and body weight, suggesting that its role in energy balance might not be as prominent as previously thought.