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Fish Transforming Growth Factor Beta 1 (TGFB1) ELISA Kit-Sandwich

Cat. No.EK3F519

Product TypeAnimal Immunoassay Kits

Size

Product Overview

BioVenic Fish Transforming Growth Factor Beta 1 (TGFB1) ELISA Kit-Sandwich is designed for the quantitative determination of Fish TGFB1 in serum, plasma, tissue homogenate, cell culture supernatant, cell extract, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich
Specificity The assay kit is specific for Fish TGFB1.
Target Species Aquaculture Species
Species Reactivity Aquaculture Species
Detection Range 6.5-400 ng/mL
Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 12%
Assay Time Around 90 min
Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell extract, and other biological fluids.

Target Information

Transforming growth factor-β1 (TGF-β1) plays a crucial role in inhibiting the activation, proliferation, and functionality of various T-cell subsets, thereby safeguarding organisms from inflammatory and autoimmune disorders that may arise from an excessive immune response. The functions of TGF-β1 in fish mainly include immunomodulation, inflammation suppression, regulation of cell proliferation and differentiation, and tissue repair. Researchers have discovered that the administration of TGF-β1 significantly hinders the proliferation of tilapia T cells, diminishes the potential for Th1/2 differentiation, and compromises cytotoxic functions, ultimately making the fish more susceptible to bacterial infections.

Target/Biomarker Fish TGFB1
Target Synonym transforming growth factor beta 1; TGFB1; transforming growth factor, beta 1; Transforming growth factor-β1; TGF-β1

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Zhang, Qian et al. "TGF-β1 suppresses the T-cell response in teleost fish by initiating Smad3- and Foxp3-mediated transcriptional networks." The Journal of biological chemistry vol. 299,2 (2023): 102843.
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