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Mouse Low Density Lipoprotein Receptor Related Protein 6 (LRP6) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Low Density Lipoprotein Receptor Related Protein 6 (LRP6) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse LRP6 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
Low Density Lipoprotein Receptor-Related Protein 6 (also known as LRP6) is a part of the Wnt-Fzd-LRP5-LRP6 complex, which activates beta-catenin signaling by promoting the aggregation of receptor-ligand complexes into ribosome-sized signalosomes. LRP6 acts as a cell-surface coreceptor in Wnt/beta-catenin signaling, crucial for bone formation. Research has indicated that mice with a heterozygous deletion of Lrp6 exhibit impaired fracture healing. The function of LRP6 in mice involves metabolic regulation, heart health, neurodevelopment, tumor biology, and a variety of other biological processes.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Burgers, Travis A., et al. "Mice with a heterozygous Lrp6 deletion have impaired fracture healing." Bone research 4.1 (2016): 1-9.