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Recombinant Swine Thrombomodulin (THBD), N-His

Cat. No.AP9C942

Product TypeAnimal Proteins

Size

Product Overview

BioVenic's Recombinant Swine Thrombomodulin (THBD), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is 61.4 kDa. The purity is>90% (SDS-PAGE).

Specifications

Type Recombinant Protein
Species Swine
Expression System E.coli
Purity >90% (SDS-PAGE)
Predicted Molecular Weight 61.4 kDa
Physical State Lyophilized
Formulation The buffer before lyophilization is PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

Target Information

Swine thrombomodulin (THBD) is an endothelial-specific type I membrane receptor that primarily functions by binding thrombin to activate protein C, which in turn degrades coagulation factors Va and VIIIa, reducing thrombin generation, and exerting anticoagulant and anti-inflammatory effects. In swine, research on THBD helps to understand its role in energy metabolism and disease, providing a basis for developing new therapeutic strategies. For example, stable expression of human THBD in porcine endothelial cells through transgenic technology can reduce inflammatory responses and prolong clotting time, which is significant in xenotransplantation . Additionally, THBD plays a key role in regulating vascular endothelial function and immune responses.

Protein Swine Thrombomodulin (THBD)
Gene ID 100157642
UniProt ID A0A8W4FEQ7

Shipping and Storage

This product is shipped with dry ice. It is recommended to aliquote as needed and store at -80°C upon receipt. Reconstituted protein solution can be stored at 4°C for 1 week, at < -80°C for 12 months.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

User Note

  1. Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL.Aliquote the reconstituted solution to minimise freeze-thaw cycles.
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