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Recombinant Rabbit Tumor Necrosis Factor (TNF), N-His

Cat. No.AP4C424

Product TypeAnimal Proteins

Size

Product Overview

BioVenic's Recombinant Rabbit Tumor Necrosis Factor (TNF), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is 21.0 kDa. The purity is> 97%.

Specifications

Type Recombinant Protein
Species Oryctolagus cuniculus (Rabbit)
Expression System E.coli
Purity > 97%
Endotoxin < 1.0 EU/μg
Predicted Molecular Weight 21.0 kDa
Physical State Lyophilized
Formulation PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.

Target Information

Rabbit Tumor Necrosis Factor (TNF) is a multifunctional cytokine with significant roles in the immune response and inflammation. TNF, particularly TNF-α, is produced by various cells, including macrophages and neurons, and is involved in cell proliferation, differentiation, apoptosis, and lipid metabolism. In rabbits, TNF-α has been shown to induce glomerular damage, highlighting its role in renal pathology. Additionally, TNF-α can alter the electrophysiological properties of rabbit hippocampal neurons, potentially contributing to cognitive changes in models of Alzheimer's disease. These findings underscore TNF's importance in both physiological and pathological processes in rabbits.

Protein Rabbit Tumor Necrosis Factor (TNF)
Protein Synonym Cachectin; TNF-alpha; Tumor necrosis factor ligand superfamily member 2
Gene ID 100009088
EC No. P04924

Shipping and Storage

This product is shipped with ice packs. Lyophilized protein can be stored at -80°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

User Note

  1. Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10 mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Aliquot the reconstituted solution to minimize freeze-thaw cycles.
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