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Recombinant Bovine Interleukin-12 Subunit Alpha (IL12A), N-His
Product Overview
BioVenic's Recombinant Bovine Interleukin-12 Subunit Alpha (IL12A), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is N/A. The purity is>97% (SDS-PAGE).
Specifications
Target Information
Bovine interleukin 12A (IL12A) is a subunit of the IL-12 cytokine, which is a crucial immunomodulatory protein in cattle. IL-12 is a heterodimer consisting of IL-12A (p35) and IL-12B (p40) chains, and it plays a significant role in promoting Th1 cell differentiation and the production of interferon-gamma (IFN-γ) by T cells and natural killer (NK) cells. This protein is essential for the development of cell-mediated immunity and helps defend against intracellular pathogens. IL-12 also has anti-tumor properties and is involved in the pathogenesis of various diseases, including autoimmune conditions and cancer. The balance of IL-12 signaling is critical for maintaining immune homeostasis and preventing excessive inflammation.
IL-12 subunit p35
Shipping and Storage
This product is shipped with dry ice. It is recommended to aliquot as needed and store at -80°C upon receipt. Reconstituted protein solution can be stored at 4°C for 1 week, at < -80°C for 12 months. Avoid repeated freezing and thawing.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Aliquot the reconstituted solution to minimise freeze-thaw cycles.