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Recombinant Rabbit Interleukin-18, N-His
Product Overview
BioVenic's Recombinant Rabbit Interleukin-18, N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is 22.3 kDa. The purity is> 97%.
Specifications
Target Information
Rabbit Interleukin-18 (IL18) is a pro-inflammatory cytokine that plays a crucial role in both innate and adaptive immune responses. It is involved in host defense against infections and regulates immune responses by stimulating the production of interferon-gamma (IFN-γ) in T helper 1 (Th1) cells and natural killer (NK) cells. IL18 also activates the transcription factor NF-κB, which is essential for the expression of various inflammatory genes. In rabbits, IL18 has been studied for its role in viral infections, such as myxomatosis, where it contributes to antiviral immunity. Additionally, IL18 is involved in epithelial barrier repair and can induce the production of other cytokines and chemokines, contributing to inflammation and immune regulation. Its multifunctional nature makes IL18 a valuable target for research in immunology and infectious diseases.
Shipping and Storage
This product is shipped with ice packs. Lyophilized protein can be stored at -80°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Aliquot the reconstituted solution to minimize freeze-thaw cycles.