This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Recombinant Mouse Thymidine Phosphorylase (Tymp), N-His
Product Overview
BioVenic's Recombinant Mouse Thymidine Phosphorylase (Tymp), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is 32.9 kDa. The purity is> 90%.
Specifications
Target Information
Mouse Thymidine Phosphorylase (Tymp) is an enzyme that plays a crucial role in nucleotide metabolism, specifically in the conversion of thymidine to thymine. This enzyme is essential for DNA synthesis and repair, making it vital for cellular function and integrity. In addition to its metabolic functions, Tymp has been implicated in various physiological processes, including immune responses and inflammation. Recent studies have shown that Tymp promotes the formation of abdominal aortic aneurysms (AAAs) by enhancing platelet activation and thrombosis while suppressing vascular smooth muscle cell (VSMC) proliferation. Tymp also plays a role in modulating the inflammatory response and matrix remodeling in AAAs. Abnormal expression of Tymp has been associated with conditions such as diabetes and certain cancers.
Shipping and Storage
This product is shipped with ice packs. Lyophilized protein can be stored at -80°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 20 mM Tris, 150 mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Aliquot the reconstituted solution to minimize freeze-thaw cycles.