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Recombinant Equine Interferon Alpha-1 , N-His
Product Overview
BioVenic's Recombinant Equine Interferon Alpha-1 , N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is 22.2 kDa. The purity is>95% (SDS-PAGE).
Specifications
Target Information
Equine interferon alpha-1 (IFN-α1) is a key component of the innate immune system, produced primarily by macrophages and involved in the first line of defense against viral infections. It exhibits antiviral activity by binding to specific receptors on cells, leading to the activation of JAK1 and TYK2, which in turn phosphorylates STAT1 and STAT2. This signaling cascade results in the formation of the ISGF3 complex, inducing the transcription of IFN-stimulated genes (ISGs), thereby modulating both innate and adaptive immune responses.
Shipping and Storage
This product is shipped with dry ice. It is recommended to aliquote as needed and store at -80°C upon receipt. Reconstituted protein solution can be stored at 4°C for 1 week, at < -80°C for 12 months.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL.Aliquote the reconstituted solution to minimise freeze-thaw cycles.