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Recombinant Mouse Leukocyte Elastase Inhibitor (Serpinb1), N-His
Product Overview
BioVenic's Recombinant Mouse Leukocyte Elastase Inhibitor (Serpinb1), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is 24.8 kDa. The purity is> 97%.
Specifications
Target Information
Mouse Leukocyte Elastase Inhibitor (Serpinb1) is a critical serine protease inhibitor that protects against excessive proteolysis in immune cells. It specifically targets neutrophil elastase and cathepsin G, preventing tissue damage from uncontrolled protease activity. Serpinb1 is highly expressed in neutrophils and macrophages, safeguarding these cells from self-inflicted harm. In mouse models, Serpinb1 deficiency results in heightened infection susceptibility and severe inflammatory responses. This protein also plays a role in regulating apoptosis and autophagy, underscoring its importance in maintaining cellular health and immune function.
Shipping and Storage
This product is shipped with ice packs. Lyophilized protein can be stored at -80°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in deionized sterile water to a concentration of 0.1-1.0 mg/mL. Aliquot the reconstituted solution to minimize freeze-thaw cycles.