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Recombinant Canine Cathepsin K (CTSK), N-His-SUMO
Product Overview
BioVenic's Recombinant Canine Cathepsin K (CTSK), N-His-SUMO is a recombinant protein expressed from E.coli. Its predicted molecular weight is 39.5 kDa. The purity is>90% (SDS-PAGE).
Specifications
Target Information
Canine cathepsin K (CTSK) is a lysosomal cysteine protease expressed in various tissues, with significant activity in osteoclasts. It is crucial for bone remodeling by degrading collagen and other bone matrix proteins. In dogs, CTSK contributes to the maintenance of skeletal health and the resorption of bone during growth and repair. This enzyme is also implicated in pathological conditions associated with increased bone resorption, such as osteoporosis and certain types of cancer that metastasize to bone.
Shipping and Storage
This product is shipped with dry ice. It is recommended to aliquot as needed and store at -80°C upon receipt. Reconstituted protein solution can be stored at 4°C for 1 week, at < -80°C for 12 months. Avoid repeated freezing and thawing.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Aliquot the reconstituted solution to minimise freeze-thaw cycles.