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Recombinant Bovine Peroxiredoxin-6 (PRDX6), N-His
Product Overview
BioVenic's Recombinant Bovine Peroxiredoxin-6 (PRDX6), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is 28.8 kDa. The purity is> 97%.
Specifications
Target Information
Bovine Peroxiredoxin-6 (PRDX6) is a multifunctional enzyme that plays a crucial role in maintaining redox homeostasis and regulating phospholipid metabolism. It possesses glutathione peroxidase activity, which helps protect cells from oxidative damage by reducing peroxides. PRDX6 also exhibits calcium-independent phospholipase A2 (iPLA2) activity, which is important for the synthesis and remodeling of lung surfactant. In bovine systems, PRDX6 is essential for protecting cells from oxidative stress and maintaining cellular integrity. It has been shown to reduce lipid peroxidation and maintain mitochondrial function, thereby supporting overall cellular health. Additionally, PRDX6 is involved in the repair of oxidized cell membranes and the activation of NADPH oxidase 2 (Nox2), which are critical for cellular defense mechanisms.
Shipping and Storage
This product is shipped with ice packs. Lyophilized protein can be stored at -80°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10 mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Aliquot the reconstituted solution to minimize freeze-thaw cycles.