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Recombinant Bovine Peroxiredoxin-6 (PRDX6), N-His

Cat. No.AP4C566

Product TypeAnimal Proteins

Size

Product Overview

BioVenic's Recombinant Bovine Peroxiredoxin-6 (PRDX6), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is 28.8 kDa. The purity is> 97%.

Specifications

Type Recombinant Protein
Species Bovine
Expression System E.coli
Purity > 97%
Endotoxin < 1.0 EU/μg
Predicted Molecular Weight 28.8 kDa
Physical State Lyophilized
Formulation PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.

Target Information

Bovine Peroxiredoxin-6 (PRDX6) is a multifunctional enzyme that plays a crucial role in maintaining redox homeostasis and regulating phospholipid metabolism. It possesses glutathione peroxidase activity, which helps protect cells from oxidative damage by reducing peroxides. PRDX6 also exhibits calcium-independent phospholipase A2 (iPLA2) activity, which is important for the synthesis and remodeling of lung surfactant. In bovine systems, PRDX6 is essential for protecting cells from oxidative stress and maintaining cellular integrity. It has been shown to reduce lipid peroxidation and maintain mitochondrial function, thereby supporting overall cellular health. Additionally, PRDX6 is involved in the repair of oxidized cell membranes and the activation of NADPH oxidase 2 (Nox2), which are critical for cellular defense mechanisms.

Protein Bovine Peroxiredoxin-6 (PRDX6)
Protein Synonym 1-Cys peroxiredoxin; Acidic calcium-independent phospholipase A2; Antioxidant protein 2
Gene ID 282438
EC No. O77834

Shipping and Storage

This product is shipped with ice packs. Lyophilized protein can be stored at -80°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

User Note

  1. Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10 mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Aliquot the reconstituted solution to minimize freeze-thaw cycles.
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