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Recombinant Mouse Podocalyxin (Podxl)
Product Overview
BioVenic's Recombinant Mouse Podocalyxin (Podxl) is a recombinant protein expressed from E.coli. Its predicted molecular weight is 28.9 kDa. The purity is> 95%.
Specifications
Target Information
Mouse Podocalyxin (Podxl) is a transmembrane glycoprotein involved in cell adhesion, migration, and differentiation. It is expressed in embryonic stem cells, hematopoietic progenitors, and vascular/lymphatic endothelial cells. Podxl is essential for maintaining the glomerular filtration barrier and is implicated in kidney diseases like focal segmental glomerulosclerosis. It is also aberrantly expressed in various tumors, promoting progression and metastasis. Podxl regulates epithelial and tumor cell motility and is involved in cholesterol biosynthesis. It is a potential therapeutic target in cancer and renal diseases.
Shipping and Storage
This product is shipped with ice packs. Lyophilized protein can be stored at -80°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in PBS or others. Aliquot the reconstituted solution to minimize freeze-thaw cycles.