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Recombinant Mouse Interferon Regulatory Factor 3 (Irf3), N-His
Product Overview
BioVenic's Recombinant Mouse Interferon Regulatory Factor 3 (Irf3), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is 49.1 kDa. The purity is> 90%.
Specifications
Target Information
Mouse Interferon Regulatory Factor 3 (Irf3) is a transcription factor that plays a crucial role in the innate immune response, particularly in the regulation of type I interferon (IFN-I) production. Irf3 is activated in response to viral infections and other pathogenic stimuli, leading to the expression of IFN-β and other antiviral genes. This activation involves phosphorylation and dimerization of Irf3, which then translocates to the nucleus to induce gene expression. In mouse models, Irf3 is essential for mounting an effective antiviral response and maintaining immune homeostasis. Abnormal expression or function of Irf3 has been implicated in various diseases, including viral infections and autoimmune disorders.
Shipping and Storage
This product is shipped with ice packs. Lyophilized protein can be stored at -80°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in deionized sterile water to a concentration of 0.1-1.0 mg/mL. Aliquot the reconstituted solution to minimize freeze-thaw cycles.