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Recombinant Mouse Complement Factor H (Cfh), N-His
Product Overview
BioVenic's Recombinant Mouse Complement Factor H (Cfh), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is 30.7 kDa. The purity is> 97%.
Specifications
Target Information
Mouse Complement Factor H (CFH) is a plasma protein involved in the regulation of the complement system. In mice, CFH plays a crucial role in distinguishing self from non-self during complement activation, preventing the destruction of host cells. It regulates the alternative complement pathway by inhibiting the formation and activity of the C3 convertase. CFH ensures that the complement system targets pathogens and foreign substances without attacking the body's own cells. Deficiencies or dysfunctions in CFH have been associated with various complement-mediated diseases, including age-related macular degeneration and atypical hemolytic uremic syndrome.
Shipping and Storage
This product is shipped with ice packs. Lyophilized protein can be stored at -80°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in deionized sterile water to a concentration of 0.1-0.5 mg/mL. Aliquot the reconstituted solution to minimize freeze-thaw cycles.