This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Recombinant Swine Thrombopoietin (THPO), N-His
Product Overview
BioVenic's Recombinant Swine Thrombopoietin (THPO), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is 20.1 kDa. The purity is>97% (SDS-PAGE).
Specifications
Target Information
Swine thrombopoietin (TPO) is a key regulator of platelet production, also known as a megakaryocyte growth-derived factor. TPO binds to the c-Mpl receptor on the surface of megakaryocytes, activating various signaling pathways such as JAK/STAT and Ras/MAPK to promote the proliferation and differentiation of megakaryocytes into platelets, thereby increasing platelet levels in circulation.
Shipping and Storage
This product is shipped with dry ice. It is recommended to aliquote as needed and store at -80°C upon receipt. Reconstituted protein solution can be stored at 4°C for 1 week, at < -80°C for 12 months.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL.Aliquote the reconstituted solution to minimise freeze-thaw cycles.