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Recombinant Mouse Coagulation Factor XII (F12), N-His
Product Overview
BioVenic's Recombinant Mouse Coagulation Factor XII (F12), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is 29.1 kDa. The purity is> 97%.
Specifications
Target Information
Mouse Coagulation Factor XII (F12) is a plasma protease that plays a role in blood coagulation and inflammation. It initiates the intrinsic coagulation pathway upon contact with negatively charged surfaces. F12 is essential for thrombus formation and stabilization, and its deficiency protects against thromboembolism without causing excessive bleeding. F12 also has roles beyond coagulation, including stimulating endothelial cell growth and neoangiogenesis, promoting neutrophil adhesion and migration, and influencing innate immunity and neuroinflammation. F12 is a potential therapeutic target for antithrombotic and anti-inflammatory therapies.
Shipping and Storage
This product is shipped with ice packs. Lyophilized protein can be stored at -80°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in deionized sterile water to a concentration of 0.1-0.5 mg/mL. Aliquot the reconstituted solution to minimize freeze-thaw cycles.