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Recombinant Mouse Chromobox Protein Homolog 3 (Cbx3), N-His

Cat. No.AP4C916

Product TypeAnimal Proteins

Size

Product Overview

BioVenic's Recombinant Mouse Chromobox Protein Homolog 3 (Cbx3), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is 22.4 kDa. The purity is> 97%.

Specifications

Type Recombinant Protein
Species Mouse
Expression System E.coli
Purity > 97%
Endotoxin <1.0 EU per 1µg (determined by the LAL method)
Predicted Molecular Weight 22.4 kDa
Physical State Lyophilized
Formulation PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.

Target Information

Mouse Chromobox Protein Homolog 3 (Cbx3) is a key epigenetic regulator involved in gene expression and chromatin dynamics. It belongs to the HP1 family and is crucial for maintaining heterochromatin structure and gene silencing. Cbx3 interacts with histone modifications like H3K9me3 and H3K27me3, influencing chromatin compaction and transcriptional repression. In developmental contexts, Cbx3 supports embryonic stem cell self-renewal and differentiation processes. Additionally, it plays a role in immune regulation, potentially aiding tumor cells in evading the immune system. Its involvement in various signaling pathways, such as Wnt/β-catenin and PI3K/AKT, highlights its multifaceted role in cellular functions.

Protein Mouse Chromobox Protein Homolog 3 (Cbx3)
Protein Synonym Heterochromatin protein 1 homolog gamma; M32; Modifier 2 protein
Gene ID 12417
EC No. P23198

Shipping and Storage

This product is shipped with ice packs. Lyophilized protein can be stored at -80°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

User Note

  1. Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10 mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Aliquot the reconstituted solution to minimize freeze-thaw cycles.
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