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Recombinant Canine CD166 Antigen (ALCAM)

Cat. No.AP1C105

Product TypeAnimal Proteins

Size

Product Overview

BioVenic's Recombinant Canine CD166 Antigen (ALCAM) is a recombinant protein expressed from E.coli. Its predicted molecular weight is 31.2 kDa. The purity is>95% (SDS-PAGE).

Specifications

Type Recombinant Protein
Species Canine
Expression System E.coli
Purity >95% (SDS-PAGE)
Endotoxin < 1 EU/µg
Predicted Molecular Weight 31.2 kDa
Molecular Weight 31.0 kDa
Physical State Lyophilized
Formulation The buffer before lyophilization is PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

Target Information

Canine CD166 antigen, also known as ALCAM, is a cell surface glycoprotein that plays a significant role in cell adhesion, particularly in immune cell interactions and the progression of various diseases, including cancer. In dogs, CD166 is involved in the modulation of cell proliferation, adhesion, migration, and invasion, which are key processes in the development and metastasis of tumors. It has also been identified as a potential marker for cancer stem cells in various types of cancer. The expression and function of CD166 can provide valuable insights into disease progression and may serve as a prognostic marker for certain conditions in dogs.

Protein Canine CD166 Antigen (ALCAM)
Protein Synonym CD166; MEMD; Activated Leucocyte Cell Adhesion Molecule
Gene ID 478550
UniProt ID O46634

Shipping and Storage

This product is shipped with dry ice. It is recommended to aliquote as needed and store at -80°C upon receipt. Reconstituted protein solution can be stored at 4°C for 1 week, at < -80°C for 12 months.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

User Note

  1. Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL.Aliquote the reconstituted solution to minimise freeze-thaw cycles.
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