Get a quote

We're excited to learn more about your project and provide you with a customized quote tailored to your needs. Please fill out the form below, and we'll get back to you as soon as possible.

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Recombinant Mouse Catenin Beta-1 (Ctnnb1), N-His

Cat. No.AP4C735

Product TypeAnimal Proteins

Size

Product Overview

BioVenic's Recombinant Mouse Catenin Beta-1 (Ctnnb1), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is 29.1 kDa. The purity is> 97%.

Specifications

Type Recombinant Protein
Species Mouse
Expression System E.coli
Purity > 97%
Endotoxin <1.0 EU per 1µg (determined by the LAL method)
Predicted Molecular Weight 29.1 kDa
Physical State Lyophilized
Formulation 100 mMNaHCO3, 500 mMNaCl, pH8.3, containing 1 mM EDTA, 1 mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.

Target Information

Mouse Catenin Beta-1 (Ctnnb1) is a dual-function protein that regulates cell-cell adhesion and gene transcription. It is a key component of the cadherin adhesion complex and acts as a signal transducer in the canonical Wnt signaling pathway. In the absence of Wnt signals, β-catenin is phosphorylated by a degradation complex and subsequently degraded by the proteasome. However, in the presence of Wnt signals, β-catenin accumulates in the nucleus, where it binds to transcription factors and regulates the expression of downstream genes. Mutations in Ctnnb1 are associated with various cancers, including colorectal cancer and hepatocellular carcinoma.

Protein Mouse Catenin Beta-1 (Ctnnb1)
Protein Synonym Beta-catenin;
Ctnnb1; Catnb
Gene ID 12387
EC No. Q02248

Shipping and Storage

This product is shipped with ice packs. Lyophilized protein can be stored at -80°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

User Note

  1. Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in deionized sterile water to a concentration of 0.1-1.0 mg/mL. Aliquot the reconstituted solution to minimize freeze-thaw cycles.
Inquiry Basket