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Recombinant Bovine Galectin (LGALS8), N-His

Name: Recombinant Bovine Galectin (LGALS8), N-His
SKU: AP9C386
Rating: 5 (1 reviews)

Cat. No.AP9C386

Product TypeAnimal Proteins

Size

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Product Overview

BioVenic's Recombinant Bovine Galectin (LGALS8), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is 43.6 kDa. The purity is>90% (SDS-PAGE).

Specifications

Type Recombinant Protein

Species Bovine

Expression System E.coli

Purity >90% (SDS-PAGE)

Endotoxin < 1 EU/µg

Predicted Molecular Weight 43.6 kDa

Molecular Weight 41 kDa

Physical State Lyophilized

Formulation The buffer before lyophilization is 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.

Target Information

Bovine galectin 8 (Gal-8) is a member of the galectin family of proteins, known for their affinity for β-galactosides. Galectins are involved in various cellular processes, including cell adhesion, migration, and immune response modulation. In cattle, Gal-8 plays a significant role in the immune system, particularly in the context of inflammation and neutrophil function. It has been studied for its potential therapeutic use in combating inflammation and its effects on neutrophil migration. Moreover, Gal-8 has been identified as a ligand for LILRB4, driving M-MDSCs which contribute to immunosuppression in the tumor microenvironment, highlighting its role in cancer progression.

Protein Bovine Galectin (LGALS8)

Protein Synonym LGALS8; PCTA1; Po66-CBP; Prostate Carcinoma Tumor Antigen 1; Lectin,Galactoside-Binding Soluble 8; Po66 carbohydrate-binding protein; Prostate carcinoma tumor antigen 1

Gene ID 506977

UniProt ID A0AAA9SWT9

Shipping and Storage

This product is shipped with dry ice. It is recommended to aliquot as needed and store at -80°C upon receipt. Reconstituted protein solution can be stored at 4°C for 1 week, at < -80°C for 12 months. Avoid repeated freezing and thawing.

Documents

Datasheet

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

User Note

Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Aliquot the reconstituted solution to minimise freeze-thaw cycles.