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Recombinant Mouse Bone Morphogenetic Protein 8B (Bmp8b), N-His

Cat. No.AP4C898

Product TypeAnimal Proteins

Size

Product Overview

BioVenic's Recombinant Mouse Bone Morphogenetic Protein 8B (Bmp8b), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is 46.7 kDa. The purity is> 90%.

Specifications

Type Recombinant Protein
Species Mouse
Expression System E.coli
Purity > 90%
Endotoxin <1.0 EU per 1µg (determined by the LAL method)
Predicted Molecular Weight 46.7 kDa
Physical State Lyophilized
Formulation 20 mM Tris, 150 mM NaCl, pH8.0, containing 1 mM EDTA, 1 mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.

Target Information

Mouse Bone Morphogenetic Protein 8B (Bmp8b) is a member of the TGF-β superfamily and plays important roles in various biological processes. It is expressed in male germ cells and trophoblast cells and is essential for the initiation and maintenance of spermatogenesis in mice. Bmp8b also regulates energy metabolism, particularly in brown adipose tissue, where it enhances thermogenesis and is involved in the neuro-vascular remodeling of adipose tissue. In addition, Bmp8b has been implicated in the progression of non-alcoholic steatohepatitis (NASH), where its deletion in mice results in reduced inflammation and fibrosis.

Protein Mouse Bone Morphogenetic Protein 8B (Bmp8b)
Protein Synonym BMP-8B; Bmp8b
Gene ID 17387
EC No. P55105

Shipping and Storage

This product is shipped with ice packs. Lyophilized protein can be stored at -80°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

User Note

  1. Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 20 mM Tris, 150 mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Aliquot the reconstituted solution to minimize freeze-thaw cycles.
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