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Recombinant Chicken Ciliary Neurotrophic Factor Receptor Subunit Alpha (CNTFR)

Cat. No.AP4C662

Product TypeAnimal Proteins

Size

Product Overview

BioVenic's Recombinant Chicken Ciliary Neurotrophic Factor Receptor Subunit Alpha (CNTFR) is a recombinant protein expressed from E.coli. Its predicted molecular weight is 40.3 kDa. The purity is>85% (SDS-PAGE).

Specifications

Type Recombinant Protein
Species Chicken
Expression System E.coli
Purity >85% (SDS-PAGE)
Predicted Molecular Weight 40.3 kDa
Physical State Lyophilized
Formulation Tris/PBS-based buffer, 5%-50% glycerol.

Target Information

Chicken Ciliary Neurotrophic Factor Receptor Subunit Alpha (CNTFR) is a key component of the CNTF receptor complex, providing receptor specificity. It is highly conserved across species and predominantly localized to the nervous system and skeletal muscle. CNTFR binds to ciliary neurotrophic factor (CNTF), which stimulates gene expression, cell survival, and differentiation in various neuronal cell types, including sensory, sympathetic, and motor neurons. In chickens, CNTFR is crucial for neuroprotection and is involved in immune responses and inflammation. Abnormal expression of CNTFR has been implicated in neurodegenerative diseases and metabolic disorders.

Protein Chicken Ciliary Neurotrophic Factor Receptor Subunit Alpha (CNTFR)
Protein Synonym CNTF receptor subunit alpha; CNTFR-alpha; Growth-promoting activity receptor subunit alpha; GPA receptor subunit alpha; GPAR-alpha
Gene ID 395885
EC No. P51641

Shipping and Storage

This product is shipped with ice packs. Lyophilized protein can be stored at -80°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

User Note

  1. Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in deionized sterile water to a concentration of 0.1-1.0 mg/mL. Aliquot the reconstituted solution to minimize freeze-thaw cycles.
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