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Recombinant Mouse Cadherin-5 (Cdh5)
Product Overview
BioVenic's Recombinant Mouse Cadherin-5 (Cdh5) is a recombinant protein expressed from E.coli. Its predicted molecular weight is 24.2 kDa. The purity is> 95%.
Specifications
Target Information
Mouse Cadherin-5 (Cdh5) is a calcium-dependent cell adhesion molecule that plays a crucial role in the formation and maintenance of endothelial cell junctions. It is highly expressed in vascular endothelial cells, where it contributes to the integrity and function of blood vessels. Cdh5 is essential for angiogenesis, the process of new blood vessel formation, and is involved in the regulation of vascular permeability and inflammation. In mouse models, Cdh5 deficiency leads to severe cardiovascular defects and embryonic lethality. Additionally, Cdh5 has been implicated in various diseases, including cancer, where it can influence tumor angiogenesis and metastasis.
Shipping and Storage
This product is shipped with ice packs. Lyophilized protein can be stored at -80°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in PBS or others. Aliquot the reconstituted solution to minimize freeze-thaw cycles.