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Recombinant Canine CD40, C-dFc
Product Overview
BioVenic's Recombinant Canine CD40, C-dFc is a recombinant protein expressed from Mammalian Expression System. Its predicted molecular weight is 46.9 kDa. The purity is>90% (SDS-PAGE).
Specifications
Target Information
Canine CD40 is a critical Type I transmembrane glycoprotein belonging to the TNF receptor superfamily. Primarily expressed on B cells, antigen-presenting cells (APCs), and macrophages, it serves as a co-stimulatory molecule that binds to CD40L (CD154). In dogs, this interaction is pivotal for B-cell proliferation, immunoglobulin class switching, and enhancing T-cell-dependent immune responses. It is a significant target in veterinary oncology and autoimmune research, particularly for developing monoclonal antibodies to treat canine lymphomas.
Shipping and Storage
This product is shipped with gel ice bags. Avoid repeated freezing and thawing. Store for 12 months at -20°C or -80°C.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Aliquote the reconstituted solution to minimise freeze-thaw cycles.