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Recombinant Bovine CD40 Ligand (CD40LG), N-His-GST
Product Overview
BioVenic's Recombinant Bovine CD40 Ligand (CD40LG), N-His-GST is a recombinant protein expressed from E.coli. Its predicted molecular weight is 48.1 kDa. The purity is> 97%.
Specifications
Target Information
Bovine CD40 Ligand (CD40LG) is a protein that plays a crucial role in the immune system of cattle. It regulates B cell function by engaging CD40 on the B cell surface, promoting immunoglobulin class switch, somatic hypermutation, and the formation of germinal centers. CD40LG is transiently expressed on T cells and other non-immune cells under inflammatory conditions, and its interaction with CD40 exerts profound effects on dendritic cells (DCs), B cells, and endothelial cells. In bovine research, CD40LG is used to study immune responses, particularly in the context of antigen presentation, T cell activation, and the regulation of B cell differentiation. It is also implicated in various diseases, including autoimmunity and cancer, where it can modulate immune cell activation and survival.
Shipping and Storage
This product is shipped with ice packs. Lyophilized protein can be stored at -80°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10 mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Aliquot the reconstituted solution to minimize freeze-thaw cycles.