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Recombinant Mouse Protein Disulfide-Isomerase (P4hb)
Product Overview
BioVenic's Recombinant Mouse Protein Disulfide-Isomerase (P4hb) is a recombinant protein expressed from E.coli. Its predicted molecular weight is 27.4 kDa. The purity is> 95%.
Specifications
Target Information
Mouse Protein Disulfide-Isomerase (P4hb) is a key enzyme involved in protein folding and disulfide bond formation in the endoplasmic reticulum (ER). It catalyzes the formation, rearrangement, and reduction of disulfide bonds in newly synthesized proteins, ensuring proper protein folding and stability. P4hb is essential for maintaining ER homeostasis and is involved in various cellular processes, including the unfolded protein response (UPR) and calcium homeostasis. Abnormal expression of P4hb has been implicated in several diseases, including osteogenesis imperfecta, a condition characterized by bone fragility. Additionally, P4hb plays a role in immune responses and has been shown to influence the function of immune cells such as T cells.
Shipping and Storage
This product is shipped with ice packs. Lyophilized protein can be stored at -80°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in PBS or others. Aliquot the reconstituted solution to minimize freeze-thaw cycles.