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Recombinant Bovine Arginase-2, Mitochondrial (ARG2), N-His

Cat. No.AP4C569

Product TypeAnimal Proteins

Size

Product Overview

BioVenic's Recombinant Bovine Arginase-2, Mitochondrial (ARG2), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is 39.6 kDa. The purity is> 97%.

Specifications

Type Recombinant Protein
Species Bovine
Expression System E.coli
Purity > 97%
Endotoxin < 1.0 EU/μg
Predicted Molecular Weight 39.6 kDa
Physical State Lyophilized
Formulation PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.

Target Information

Bovine Arginase-2, Mitochondrial (ARG2) is a key enzyme involved in L-arginine metabolism, primarily located in the mitochondria. It converts L-arginine to urea and L-ornithine, which can be further metabolized to produce polyamines essential for cell proliferation. ARG2 plays a significant role in immune regulation, promoting pro-inflammatory responses in macrophages through mitochondrial reactive oxygen species (ROS) production. In bovine systems, ARG2 is implicated in various cellular functions, including the regulation of nitric oxide (NO) synthesis and the maintenance of mitochondrial function. It also contributes to the immune evasion of pathogens and the regulation of inflammation-related signaling. Additionally, ARG2 has been shown to influence glucose metabolism and insulin sensitivity, highlighting its importance in metabolic processes.

Protein Bovine Arginase-2, Mitochondrial (ARG2)
Protein Synonym Arginase II; Type II arginase
Gene ID 518752
EC No. G3MWN1

Shipping and Storage

This product is shipped with ice packs. Lyophilized protein can be stored at -80°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

User Note

  1. Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10 mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Aliquot the reconstituted solution to minimize freeze-thaw cycles.
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