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Rabbit Anti-Rat Alpha 2-Antiplasmin (a2PI) Polyclonal Antibody

Name: Rabbit Anti-Rat Alpha 2-Antiplasmin (a2PI) Polyclonal Antibody
SKU: VD1N370
Rating: 5 (1 reviews)

Cat. No.VD1N370

Product TypeAnimal-targeted Antibodies

Size

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Product Overview

BioVenic rabbit polyclonal antibody is specific for rat alpha 2-antiplasmin. It is affinity purified by protein A. It can be applied to WB, IHC, ICC and IP assays of rat alpha 2-antiplasmin.

Specifications

Application WB; IHC; ICC; IP

Clonality Polyclonal

Classification Primary Antibody

Clone A11N19

Host Rabbit

Target Species Rat

Species Reactivity Rat

Specificity Rat Alpha 2-Antiplasmin

Isotype IgG

Immunogen Recombinant protein of rat alpha 2-antiplasmin

Purification Protein A Purified

Concentration 0.5 mg/mL

Conjugation Unconjugated

Preservative and Stabilizer 0.02% Sodium Azide

Buffer Phosphate Buffered Saline, pH 7.4, with 50% Glycerol

Physical State Liquid

Target Information

Rat Alpha 2-Antiplasmin (a2PI) is a serine protease inhibitor that plays a crucial role in regulating fibrinolysis. It forms a covalent complex with plasmin, thereby inhibiting its proteolytic activity and preventing excessive degradation of fibrin clots. a2PI is synthesized in the liver and circulates in the blood, where it helps maintain the balance between coagulation and fibrinolysis. In rat models, a2PI is essential for preventing pathological bleeding and maintaining vascular integrity.

Target Rat Alpha 2-Antiplasmin

Target Synonym SERPINF2; AAP; A2-PI; API; PLI; A2AP; Alpha-2-Plasmin Inhibitor; Serpin Peptidase Inhibitor Clade F Member 2; Pigment Epithelium Derived Factor

Gene ID 287527

UniProt ID Q68G45

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 2 years). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

Datasheet

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

Singh, Satish, et al. "Alpha2-antiplasmin: the devil you don't know in cerebrovascular and cardiovascular disease." Frontiers in Cardiovascular Medicine 7 (2020): 608899.