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Rabbit Anti-Mouse Membrane Spanning 4 Domains Subfamily A Member 1 (CD20) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for mouse membrane spanning 4 domains subfamily A member 1. It is purified by protein A/G. It can be applied to WB, IHC, ICC and IP assays of mouse membrane spanning 4 domains subfamily A member 1.
Specifications
Target Information
Mouse membrane-spanning 4-domains subfamily A member 1 (MS4A1), also termed CD20, is a 297-residue tetraspan phosphoprotein that threads through the plasma membrane four times, creating two extracellular loops of 42 and 72 residues and cytoplasmic N- and C-termini. The larger loop harbors an evolutionarily conserved N-linked glycosylation site and a disulfide bond that stabilize a compact α-helical bundle. Expressed exclusively on the surface of developing and mature B lymphocytes, MS4A1 localizes to lipid rafts and microvilli. Antibodies raised against the larger extracellular loop detect native MS4A1 with negligible cross-reactivity to other MS4A family members, enabling precise immunoblot, immunohistochemistry and flow-cytometric detection in mouse lymphoid tissues and cultured B cells.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.