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Rabbit Anti-Mouse Tumor Necrosis Factor Related Apoptosis Inducing Ligand (TRAIL) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for mouse tumor necrosis factor related apoptosis inducing ligand. It is purified by protein A. It can be applied to WB, IHC, ICC and IP assays of mouse tumor necrosis factor related apoptosis inducing ligand.
Specifications
Target Information
Mouse tumor-necrosis-factor-related apoptosis-inducing ligand (TRAIL) is a 24 kDa type-II trans-membrane glycoprotein that targets death receptors DR4 and DR5 on transformed or virus-infected cells, forming a homotrimer which recruits FADD and caspase-8 to trigger extrinsic apoptosis. Its conserved receptor-binding TNF-homology domain presents a unique, species-restricted trimeric epitope ideal for antibody generation; anti-TRAIL immunoreagents detect membrane-bound and soluble forms in serum, tissue homogenates and cultured cells without cross-reacting with other TNF-family ligands, providing a precise read-out of death-receptor signaling and immune surveillance.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.