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Rabbit Anti-Guinea Pig Insulin (INS) Polyclonal Antibody

Cat. No.VD3N719

Product TypeVeterinary Antibodies

Size

Product Overview

BioVenic rabbit polyclonal antibody is specific for guinea pig insulin. It is purified by protein A. It can be applied to WB, IHC, ICC and IP assays of guinea pig insulin.

Specifications

Application WB; IHC; ICC; IP
Clonality Polyclonal
Classification Primary Antibody
Clone C2N119
Host Rabbit
Target Species Guinea Pig
Species Reactivity Guinea Pig
Specificity Guinea Pig Insulin
Isotype IgG
Immunogen Recombinant protein of guinea pig insulin
Purification Purified by Protein A
Concentration 0.5 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.05% Proclin 300
Buffer 0.01M Phosphate Buffered Saline, pH 7.4, with 50% glycerol
Physical State Liquid

Target Information

Guinea-pig insulin is a 5.8 kDa two-chain peptide hormone processed from pro-insulin in pancreatic β-cells. It targets the insulin receptor tyrosine-kinase on adipose, muscle and liver membranes, initiating PI3K/MAPK cascades that drive glucose uptake, glycogen synthesis and lipogenesis. Its A- and B-chain disulfide-linked structure presents a unique, species-restricted epitope ideal for antibody generation; anti-insulin immunoreagents detect circulating and stored hormone in plasma, islet homogenates and fixed pancreatic sections without cross-reacting with guinea-pig IGF-1 or pro-insulin, providing a precise read-out of β-cell function and metabolic control.

Target Guinea Pig Insulin
Gene ID 397415
UniProt ID P01329

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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