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Rabbit Anti-Mouse Furin (FUR) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for mouse furin. It is purified by protein A. It can be applied to WB, IHC, ICC and IP assays of mouse furin.
Specifications
Target Information
Mouse furin is a 94 kDa type-I transmembrane proprotein convertase whose subtilisin-like catalytic domain cleaves RX(K/R)R motifs in the TGN and at the cell surface. A solvent-exposed 16-aa "HGK" loop (aa 303-318) between the S1 and S3 pockets folds into a β-hairpin unique among mouse PCs, presenting a conformational epitope preserved after paraformaldehyde fixation. Affinity-purified antibodies targeting this loop trace native furin in Golgi membranes, neuronal growth cones, and adrenal medulla, delivering crisp perinuclear rings and single-band clarity on immunoblots with no cross-reaction to PC5/6 or PC7.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
