This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Rabbit Anti-Mouse Density Enhanced Phosphatase 1 (DEP1) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for mouse density enhanced phosphatase 1. It is purified by protein A. It can be applied to WB and IHC assays of mouse density enhanced phosphatase 1.
Specifications
Target Information
Mouse density-enhanced phosphatase 1 (DEP-1) is a 220 kDa receptor-like protein tyrosine phosphatase whose extracellular fibronectin-type III repeats cluster at cell-cell contacts, while the single intracellular catalytic domain targets phosphorylated tyrosines on growth-factor receptors and adherens-junction components. A solvent-exposed "KNRY" motif (aa 1165-1178) within the juxtamembrane wedge is unique among PTPRJ family members, presenting a conformational epitope accessible in both native and fixed tissues. Affinity-purified antibodies directed against this sequence trace DEP-1 in lung endothelium, mammary epithelium, and fibroblast focal adhesions, delivering crisp membrane staining and single-band specificity on immunoblots with no cross-reaction to DEP-2 or CD45.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.