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Rabbit Anti-Bovine Tissue Factor (TF) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for bovine tissue factor. It is purified by protein A/G. It can be applied to WB, IHC, ICC and IP assays of bovine tissue factor.
Specifications
Target Information
Bovine tissue factor (TF, coagulation factor III) is a 295-residue type I transmembrane glycoprotein whose extracellular Ig-like domain (residues 33-134) binds factor VIIa and phospholipid, while a single transmembrane helix anchors the protein to vascular smooth-muscle cells, fibroblasts and pericytes. A short 22-aa cytoplasmic tail contains a lysine-rich motif that associates with actin. Constitutively expressed in adventitia and organ capsules, TF localizes to cell surfaces and extracellular vesicles. Antibodies raised against the extracellular domain or cytoplasmic peptide detect native, glycosylated and truncated forms with negligible cross-reactivity to other coagulation factors, enabling selective immunoblot and immunohistochemical visualization in bovine tissue homogenates and sections.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.